摘要
目的 探讨冠状动脉狭窄或闭塞性病变及早恢复前向血流后对QT间期离散度 (QTd、QTcd)的长期影响及其与心功能的关系。方法 观察急诊经皮冠状动脉介入治疗术 (PCI)术前、随访术后不同时间的QTd、QTcd及心功能的变化。结果 与经皮冠状动脉球囊成形术 (PTCA)和支架植入术前比较 ,术后 2~ 4h的QTd、QTcd虽有下降趋势 ,但无统计学意义 ,而术后 1周、6个月的QTd、QTcd显著减低 ,其后的QTd、QTcd亦无明显变化 ;但出现左心功能不全 (EF≤ 4 0 % )者QTd较之心功能正常者明显延长。结论 急诊PCI治疗使缺血心肌再灌注获得的QTd降低即改善心室复极不均一性的作用是持续的。
Objective To investigate the anterior-blood recovery of coronary artery in emergency department on the long-term influence of QTd or QTcd as well as the relationship with heart function.Methods To observe and follow up the variety of QT dispersion (QTd)and cardiac function in the cases who underwent emergency percutaneous coronary intervention (PCI).Results Compared with the data of cases before percutaneous transluminal coronary angioplasty (PTCA)and stunts implantation,there was no significant difference in QTd and QTcd in 2~4 hours post-operation, though QTd and QTcd showed a declined trend,and a significant descent of QTd and QTcd was found in 1-week and 6-month post-operation.There was a significant prolongation of QTd and QTcd in the cases with heart failure (EF≤40%)compared with the cases with normal heart function.Conclusions The effect of emergency PCI treatment on QTd descent obtained from reperfusion of ischemic myocardium or improvement of ventricular inhomogeneous repolarization was persistent.The heart function was an important factor which can affect QTd prolongation.
出处
《中国急救医学》
CAS
CSCD
北大核心
2004年第6期396-397,共2页
Chinese Journal of Critical Care Medicine
关键词
QT间期离散度
急诊
经皮冠动脉球囊成形术
冠状动脉内支架植入术
QT dispersion
Emergency
Percutaneous transluminal coronary angioplasty(PTCA)
Percutaneous coronary intervention(PCI)