摘要
心肌乏氧显像是通过评价心肌氧供与氧耗平衡而提供检测缺血但存活心肌的一种非侵入性检查方法,而且是评价血管生成及心肌病的发生和发展的有用指标。动物实验和已有的临床研究表明,18F标记的硝基咪唑类化合物、有广泛应用前景的99Tcm标记的咪唑类化合物以及其他新的乏氧显像剂已用于评价缺血存活心肌。广泛的临床应用有待于进一步实验及临床研究。
Myocardial hypoxia imagings provide noninvasive approaches for the detection of myocardial ischemia, dedication of the potential role of hypoxia in development of angiogenesis and cardiomyopathy by the detection of balance of flow and oxygen consumption. Animal experiments and clinical trials show fluoromisonidazole and technetium-99m labeled nitroimidazoles and novel class hypoxia imaging markers have been developed for imaging of regional myocardial ischemia. The true clinical applications rely on future experimental and clinical studies.
出处
《国外医学（放射医学核医学分册）》
2004年第3期113-117,共5页
Foreign Medical Sciences(Section of Radiation Medicine and Nuclear Medicine)
