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肿瘤细胞多药耐药与神经酰胺的糖基化 被引量:2

Multidrug resistance of tumor cells and ceramide glycosylation
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出处 《中国现代普通外科进展》 CAS 2004年第3期139-141,共3页 Chinese Journal of Current Advances in General Surgery
基金 山东省卫生厅科研基金资助项目 (0 5 2 12 0 2 )
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  • 1Bleicher RJ,Cabot MC.Glucosylceramide synthase and apoptosis[J].Biochim Biophys Acta,2002,1585(2-3):172-178.
  • 2Sietsma H,Veldman RJ,KoK JW.The involvement of sphingolipids in multidrug resistance[J].J Membr Biol,2001,181(3):153-162.
  • 3Lavie Y,Cao H,Bursten SL,et al.Accumulation of gulcosylceramide in multidrug-resistant cancer cells[J].J Biol Chem,1996,271(32):19530-19536.
  • 4Shirahama T,Sweeney EA,Sakaura C,et al.In vitro and in vivo induction of apoptosis by sphingosine and N,N-dimethylspingosin in human epidermoid carcinoma KB-3-1 and its multidrug-resistant cells[J].Clin Cancer Res,1997,3(2):257-264.
  • 5Pean LA,Fuks Z,Kolesmick R..Stress-induced apoptosis and the sphingomyelin pathway[J].Bionchem Pharmacol,1997,53(5):615-621.
  • 6Siegel DS,Zhang X,Feinman R,et al.Hexamethylene bisacetamide induces prograed cell death (apoptosis)and down-regulates bcl-2 expression in human myeloma cells[J].Proc Natl Acad Sci USA,1998,95:162-166.
  • 7Lucci A,Giuliano AE,Han TY,et al.Ceramide toxicity and metabolism differ in wild-type and multidrug-resistant cancer cells[J].Int J Oncol,1999,15(3):535-540.
  • 8Lucci A,Han TY,Liu YY,et al.Modification of ceramide metabolism increases cancer cell sensitivity to cytotoxic[J].Int J Oncol,1999,15(3):541-546.
  • 9张健,张积仁,袁亚维,赵燕,林学颜.中性鞘糖脂在KBv_(200)细胞的表达及其与多药耐药性的关系[J].中华肿瘤杂志,2001,23(2):111-114. 被引量:4
  • 10Shabbits JA,Mayer LD,P-glycoprotein modulates ceramide-mediated sensitivity of human breast cancer cells to tubulin-binding anticancer drugs[J].Mol Cancer Ther,2002,1(3):205-213.

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