急性脑卒中诱发下呼吸道感染的因素分析

Risk Factors of Lower Respiratory Tract Infection Following Stroke

目的 研究急性脑卒中患者发生下呼吸道感染的危险因素。方法 回顾性调查急性脑卒中诱发下呼吸道感染的病例 ,单因素分析 ,多因素Logistic回归分析其危险因素。结果 单因素分析发现年龄、昏迷程度、咳嗽反射差、吞咽困难、呼吸道疾病、吸烟、入住ICU、气管插管机械通气、留置导尿、留置胃管、H2 受体阻滞剂 /制酸剂、联合应用 2种以上抗生素与下呼吸道感染的发生显著相关。多因素Logistic回归分析发现高龄、昏迷程度深、气管插管机械通气、咳嗽反射差、联合应用 2种以上抗生素与下呼吸道感染发生高度相关。结论 高龄、昏迷程度深、气管插管机械通气、咳嗽反射差、联合

Objective To analyse the risk factors of lower respiratory tract infection following stroke. Methods Using Logistic regression,retrospective study was made on 60 cases of stroke with lower respiratory tract infection. Results Single regression analysis indicated that following variables were associated with lower respiratory tract infection:age≥65,coma (GSC≤8),weak cough reflex,dysphagia,respiratory disease,smoking,admission in ICU,intubation and mechanical ventilation,urinary catheter,H2_receptor antagonist/antacids,two or more antibiotics. Multiple regression analsis indicated that following factors were strongly related:age≥65,coma (GSC≤8),intubation and mechanical ventilation,weak cough reflex,and two or more antibiotics. Conclusions The high risk factors of lower respiratory tract infection following stroke are:age≥65,coma (GSC≤8),intubation and mechanical ventilation,weak cough reflex,and two or more antibiotics.