摘要
1980年,美国的Poiesy和日本的Miyoshi等先后发现人类第一个C型逆转录病毒,后国际上统一命名为人嗜T淋巴细胞Ⅰ型病毒(HTLV-1)。这类病毒以人T_4细胞亚群为靶细胞,并与成人T细胞白血病有病原学关系。1985年,Gessain等报告在热痉挛性瘫痪病人(Tropical Spastic Paraparesis,TSP)血清和脑脊液中查出HTLV-Ⅰ抗体,1986年又在Colombia、Jamaica、Trinidad、Tobago和Ivory Coast等一些国家和地区,也发现某些慢性脊髓神经病变患者(症状相似于TSP病人)的血清和脑脊液中有HTLV-Ⅰ抗体存在。
244 sera from patients with various neurological diseases were tested. 5 of them had detectable antibody to HTLV-1 confirmed by Westem blot test. In the 5 cases, 2 were diagnosed clinically as neurological myelopa-thies and 3 were other neurological diseases.This is the first report of patients with HTLV-l virus associated neurologica disease in China.Neurologica
出处
《病毒学报》
CAS
CSCD
北大核心
1993年第4期382-385,共4页
Chinese Journal of Virology
基金
卫生部重点科技资助
部分为世界实验室(World Lab)资助
