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二氢吡啶类钙拮抗剂在老年高血压中的应用 被引量:5

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摘要 高血压的发病随年龄而增加,在老年人群相当普遍,65岁以上的人群有慢性高血压的超过50%.越来越多的临床试验表明降低血压值与减少心血管事件是普遍相关的,对于心血管病的患病率和病死率来说,高血压,尤其是收缩期高血压是老年人群的独立的可治疗危险因素[1,2].钙离子的跨膜转运作为全身血管阻力增加的重要调节因子,而血管阻力增加是高血压状态的主要特征,钙拮抗剂通过直接舒张血管平滑肌而具有血管扩张作用,它已成为降压治疗的一线用药.
出处 《解放军保健医学杂志》 2004年第2期123-125,共3页 Journal Of Health Care And Medicine in Chinese Pla
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