摘要
介绍了头孢克肟的抗菌活性。综述了头孢克肟侧链的合成方法 ,提出了从氯乙酰乙酸乙酯为原料经肟化、缩合 2步反应合成头孢克肟侧链是一条适合于工业化生产的工艺路线。参考文献 2
The medical properties of Cefixime are introduced. Synthesis of Cefixime side chain several synthetic methods from different raw materials were discussed in detail. A preparation method sutiable for industrial application was also suggested. 20 References were quoted.
出处
《合成化学》
CAS
CSCD
2004年第4期348-350,364,J002,共5页
Chinese Journal of Synthetic Chemistry
关键词
头孢克肟
合成
铡链
综述
Cefixime
synthesis
review
side chain
