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鼻咽癌放疗后肿瘤消退相关因素临床分析 被引量:4

Relation Agent of Tumor Extinction of Nasopharyngeal Carcinoma after Radiotherapy
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摘要 目的 分析鼻咽癌放疗后影响肿瘤消退的临床因素。方法  77例鼻咽癌根治性放疗后行CT检查动态观察 2年 ,至肿瘤消退或形态不再改变为止。结果 放疗后 2年其肿瘤消退率为 84 .4 % (6 5 /77)。统计学采用二项分类Logistic回归分析 ,生长类型、T分期、N分期、颅底骨破坏数目、新辅助化疗、原发灶剂量是影响肿瘤消退的主要因素 (P <0 .0 5 )。结论 明确影响肿瘤消退临床因素 ,对合理制定放疗计划 ,判断预后 ,改善生存率具有重要意义。 Objective To analyze the factor of tumor subsidizing of nasopharyngeal carcinoma after radiotherapy. Methods Seventy-seven nasopharyngeal carcinoma patients has been performed computer tomography scan and dynamic observed for 2 years after radical radiotherapy,until tumor extinction or form was not happened diversification. Results Tumor extinction rate is 84.4% (65/77) post radiotherapy after 2 years. Through binary Logistic regression check,growth type,T staging,N staging,numerical of base of skull destruction,neoadjunvant chemotherapy and tumor dosage of original locus is main agent to effect tumor extinction ( P < 0.05 ).Conclusion To definitude effecting clinical factor of tumor extinction,it is important to formulate radiotherapy plan reasonable,estimate prognosis and amelioration survival rate.
作者 崔巍 胡国清
出处 《肿瘤防治研究》 CAS CSCD 2004年第5期301-303,共3页 Cancer Research on Prevention and Treatment
关键词 鼻咽癌 放疗 肿瘤 临床资料 适应症 Nasopharyngeal carcinoma Radiotherapy Tumor extinction
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