Xa21转基因大米的营养学评价

Nutrition assessment of transgenic rice

目的 观察转基因大米对幼鼠喂养的营养学功效。方法 将初断乳Wistar大鼠按雌、雄分别随机分为三组 ,即转基因大米组、非转基因大米组和AIN93G正常对照组。饲相应饲料 ,自由进食 ,喂养 2 8天。观察指标 :大鼠进食量、蛋白质功效比、体重、身长、血常规、血生化、脏体比值和骨密度。结果 雄性组 :转基因大米组除肝 体比高于非转基因大米组外 ,其他所有观察指标和非转基因大米组均无显著性差异。雌性组 :转基因大米组肝 体比、血钙和干骺端骨密度高于非转基因大米组 ,其他所有指标转基因大米组和非转基因大米组均无差异。与正常对照组相比 ,转基因大米组血钙和干骺端骨密度显著增加。结论 转基因大米 2 8天动物喂养实验未发现有明显毒副作用。

Objective To observe the nutrition effects between transgenic rice and non-transgenic rice. Methods Wistar rats were divided into three groups according to their sex respectively: transgenic rice group, non-transgenic rice group and AIN93G normal control group. They were fed with corresponding food for 28 days. Indicator as follows: food intake, protein effective ratio, body weight, body length, blood routine test, blood biochemistry test, organ index and bone density. Results In male groups, expect that liver/body ratio was higher in transgenic rice group than that in non-transgenic rice group, all other indicators had no significant difference each other. In female groups, liver/body weight ratio, blood calcium and bone density were higher in transgenic group than those in non-transgenic group. All other indicators had no significant difference between transgenic rice group and non-transgenic rice group. Body weight, bone density and blood calcium were higher and liver/body weight ratio had no significant difference in transgenic rice group than those in AIN93G group. Conclusion Transgenic rice had good nutrition effects on rat development and no toxicity and adverse effects were found in transgenic rice group.