快速预制随意皮瓣的实验研究与临床应用

Experimental studies and clinical application of quickly prefabricated random skin flap

目的 在 2 4h内扩大随意皮瓣长宽比例 ,以满足临床特殊需要。方法 选择SD大白鼠、北京白小猪行动物实验 ,分别设实验组和对照组 ,按一定方式预制皮瓣 ,并监测皮瓣微循环参数(PU值 ) ,实验组动物行预制皮瓣训练 ,对照组无训练 ,根据PU值检测数据监控皮瓣微血流灌注 ,2 4h内达到超长宽比例随意皮瓣成活水平 ,并应用于临床。结果 实验组皮瓣存活面积较对照组显著增大 ,达到实验设计目的。在烧伤、整形、修复重建临床应用中增加了特殊部位损伤的修复手段。结论 快速预制随意皮瓣的方法能使随意皮瓣的适用范围扩大 ,能在较短的时间里增大皮瓣的长宽比例 ,大大提高随意皮瓣的成活几率。

Objective To enlarge the ratio of length to width of a prefabricated random skin flap in a short period,in order to meet a special clinical need. Methods A white rat and a white mini-pig was chosen for an animal model for the experiment. They were divided into the experimental group and the control. The prefabricated flap was formed as the planned design. In the experimental group,the flaps were treated with a desired pressure in certain intervals at the planned part of the flap. We estimated and inspected the digitized perfusion of flap microcirculation,and made overcong and wide random skin flap survive within 24hours,and this technique was finally used for the clinical wound treatment. Results As expected,the survival area of the flap in the experimental group was significantly larger than the control. This technique was successfully used to repair the defects of the special sites in plastic and reconstructive surgery. Conclusion the method of quickly prefabricated random flap could enlarge the ratio of length to width of the flap and put the flap in shape in short time. With the digitized estimating and inspecting,this method could obviously improve the survival area of the random flap and could also be very useful for the clinical treatment. ;