补充复力康合剂对训练大鼠运动能力及血清T、C、GH水平的影响

Effects of Chinese Herbs "Fu Li Kang" on Serum T,C,GH of Rats

目的 :观察补充复力康合剂对训练大鼠运动能力的作用 ,探讨雌性成年大鼠GH/C比值与雄性成年大鼠T/C比值与运动能力的关系。方法 :成年SD大鼠 ,雄性 30只 ,雌性 31只 ,随机分为雄性安静对照组、雄性运动对照组、雄性运动服药组、雌性安静对照组、雌性运动对照组和雌性运动服药组 6组。运动对照组和运动服药组每天负重 4 %力竭游泳 ,每周游泳 6天 ,观察游泳时间。运动服药组每天灌喂复力康合剂 (10 8g生药 /kg体重 ) 1次 ,安静对照组和运动对照组则按同等比例灌喂蒸馏水 1次。共 4周。取材当日完成运动负荷后取血清 ,测定睾酮 (T)、生长激素 (GH)和皮质醇 (C)。结果 :长期游泳训练导致雄性大鼠血清T水平明显降低 ,而雌性大鼠则主要表现为GH的降低 ,服用复力康合剂后能提高雄性大鼠血清T水平和雌性大鼠GH的水平。运动服药组力竭游泳时间较运动对照组明显延长。以上结果提示补充复力康合剂对机体运动能力有良性作用。

Objective To observe the effect of Chinese herbs 'Fu Li Kang' on serum testosterone (T), cortisol (C) and growth hormone (GH) of swimming rats. Methods Adult rats (male 30, female 31) were randomly divided into six groups: male blank group (M1,n=9), male swimming group(M2,n=9), male swimming and herbs group(M3,n=12), female blank group (F1,n=9) , female swimming group (F2,n=8), female swimming and herbs group (M3,n=14). Rats of M2, M3, F2, F3 were subjected to 4 weeks (6d/w) exhaustive swimming exercise and the swimming time of each group was recorded. In contrast with other group , rats in M3 and F3 were fed with Chinese herbs ' Fu Li Kang' once a day during the experiment. All rats were killed immediately after the last exercise to detect the level of serum T, GH and C. Results Exhaustive swimming exercise caused the decrease of serum T level of male rats and serum GH level of female rats. Chinese herbs 'Fu Li Kang' could effectively increase serum T level of male rats, serum GH level of female rats as well as the swimming time. These results suggested that Chinese herbs 'Fu Li Kang' had postive effect on improving exercise ability.