硫酸西索米星氯化钠注射液中氯化钠含量测定方案的改进

The improvement of determination of sodium chloride in sisomicin sulfate and sodium chloride injection

目的 探讨硫酸西索米星氯化钠注射液中氯化钠含量测定的最佳方案。方法 利用双氧水氧化其中的辅料及主药 ,从而消除干扰。结果 实验结果明显优于原始方案。结论 改进后的方案更适合硫酸西索米星氯化钠注射液中氯化钠含量的测定。

The excipients in sisomicin sulfate and sodium chloride injection have a great influence on the determination of sodium chloride.In this method hydrogen peroxide is used to oxidate the excipient and major componet to eliminate the disturb of the excipients.Obviously the method exceeds the precending one.