1Stehouwer CAD, Fischer HRA, Van Kui jk AWR, et al. Endothelial dysfunction precedes development of microalbuminuria in IDDM[J]. Diabetes, 1995, 44: 561-564.
2Veves A, Akbari CM, Primavera J, et al. Endothelial dysfunction and the expression of endothelial nitric oxide synthase in diabetic neuropathy, vascular disease and food ulcrration[J]. Diabetes, 1998, 47: 457-463.
3GUO ZX, REN GQ. The relationship between endothelium and hypertension converzyne diabetes hephropathy [J]. Zhongguo Xiandai Yixue Zazhi, 2000, 10(7): 52-53.
4Andem S, rennkehg, Garcia DL, et al. Short and long term effects of antihypertensive therapy in diabetic rat [J]. Kidney Int, 1989, 36: 526-536.
5Kone BC. Nitric oxide in renal health and disease[J]. Am J Kid ney Dis, 1997, 30: 311-314.
3Gorin Y,Block K,Hernandez J,et al.Nox4 NADPH oxidase mediates hypertrophy and fibronectin expression in the diabetic kidney.J biol chem 2005;280(47):39616-39626
4Sonta T,Inoguchi T,Tsubouchi H,et al.Evidence for contribution of vascular NADPH oxidase to increased oxidative stress in animal models of diabetes and obesity.Free Radic Biol Med 2004;37(1):115-123
5Lu SC.Ragulation of glutathione synthesis.Curr Top Cell Regul 2000;36:95-116
6Kakkar R,Mantha SV,Radhi J,et al.Antioxidant defense system in diabetic kidney:a time course study.Life Sci 1997;60(9):667-79
7Bruner SD,Norman DP,Verdine GL.Structural basis forrecognition and repair of the endogenous mulagen 8-oxoguaninein DNA.Nature 2000;403(6772):859-866
8Schwemmer M,Fink B,Kockerbauer R,et al.How urine analysis reflectsoxidative stress-nitrotyrosine as a potential marker.Clin Chimica Acta 2000;297(1-2):207-216
9Leinonen J,Lehtimaki T,Toyokuni S,et al.New biomarker evidence of oxidative DNA damage in patients with non-insulin-dependent diabetes mellitus.FEBS Lett 1997;417(1):150-152
10Ceriello A,Mercuri F,Quagliaro L,et al.Detection of nitrotyrosine in the diabetic plasma:evidence of oxidative stress.Diabetologia 2001;44(7):834-838