妊娠高血压综合征血液黏度等指标的改变

The study on changes of blood viscosity index in patients with pregnancy-induced hypertension

目的研究妊娠高血压综合征(妊高征)患者血液黏度等指标的变化。方法对80例妊高征患者、36例正常妊娠组和40例正常非妊娠组,应用全自动血黏度仪测定全血黏度、血浆黏度、全血还原黏度(低切)。温氏法测血沉及红细胞压积。结果中、重度妊高征患者组的全血黏度、血浆黏度、血沉及红细胞压积均明显高于正常妊娠组和正常非妊娠组,并具有明显的统计学意义(P<0.05);而轻度妊高征组不如中、重度妊高征患者组的全血黏度等指标变化明显。在全血还原黏度(低切)上各个实验组没有明显的统计学意义。结论妊高征患者的血液黏度、血沉及红细胞压积明显升高,而全血还原黏度(低切)没有升高。

Objective To study the changes of blood viscosity etc. in patients with pregnancy-induced hypertension (PIH). Methods Whole blood viscosity, plasma viscosity and whole blood reductive viscosity (low shear rate) were tested using automatic blood viscosity instruments in 80 PIH patients, 36 normal pregnancy women and 40 normal non-pregnancy women. At the same time, Erythrocyte sedimentation rates (ESR) and hematocrit (Hct) were detected by Wintrobe-landsbery method. Results Whole blood viscosity, plasma viscosity, ESR and Hct in medium and severe PIH patients were significantly higher than normal pregnancy women and normal non-pregnancy women (P<0.05); however, in mild PIH patients, the changes of whole blood viscosity was not significant compared with medium and severe PIH patients. In whole blood reductive viscosity(low shear rate), no significant difference was found among each experimental group. Conclusions In PIH patients, blood viscosity, plasma viscosity, ESR and Hct significantly increased, except for whole blood reductiveviscosity (low shear rate)