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细胞周期调控因子异常与食管癌 被引量：1

Advance of cell cycle regulatory factors in esophageal carcinoma
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摘要 细胞周期是细胞生命活动的基本过程 ,其调控因子的异常与细胞癌变关系密切。食管癌发生发展过程中 ,多种细胞周期调控因子表达异常 ,并与临床病理特征有密切关系。
作者 李丽 齐凤英
机构地区 河北医科大学病理学教研室
出处 《国外医学（肿瘤学分册）》 2004年第6期456-459,共4页 Foreign Medical Sciences (Cancer Section)
关键词 细胞周期 基因表达调控 食管肿瘤 细胞周期蛋白 细胞周期蛋白质依赖激酶类
分类号 R735.1 [医药卫生—肿瘤]
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参考文献22

  • 1Matsumoto M, Furihata M, Ishikawa T, et al. Comparison of deregulated expression of cyclinD1 and cyclinE with that of cyclin-dependent kinase 4 (CDK4) and CDK2 in human oesophageal squamous cell carcinoma. Br J Cancer, 1999,80(1-2) :256-261.
  • 2Ralhan R,Mathew R,Arora S,et al. Frequent alteration in the expression of tumor suppressor genes p16INK4A and pRb in esophageal squamous cell carcinoma in the Indian population. J Cancer Res Clin Oncol, 2000,126 (11): 655-660.
  • 3Takeuchi H,Ozawa S,Ando N,et al. Cell-cycle regulators and the ki-67 labeling index can predict the response to chemoradiotherapy and the survival of patients with locally advanced squamous cell carcinoma of the esophagus. Ann Surg Oncol, 2003,10(7): 792-
  • 4Ohbu M, Kobayashi N, Okayasu I. Expression of cell cycle regulatory proteins in the multistep process of oesophageal carcinogenesis:stepwise over-expression of cyclinE and p53, reduction of p21(WAF1/CIP1) and dysregulation of cyclin D1 and p27 (KIP1).Hist
  • 5Shiozaki H,Doki Y,Yamana H,et al. A multi-institutional study of immunohistochemical investigation for the roles of cyclinD1 and Ecadherin in superficial squamous cell carcinoma of the esophagus. J Surg Oncol, 2002,79 (3): 166-173.
  • 6Matsumoto M, Furihata M, Ishikawa T, et al. Comparison of deregulated expression of cyclinD1 and cyclinE with that of cyclin-dependent kinase 4 (CDK4) and CDK2 in human oesophageal squamous cell carcinoma. Br J Cancer, 1999,80(1-2) :256-261.
  • 7Shamma A, Doki Y, Shiozaki H, et al. Effect of cyclinD1 and associated proteins on proliferation of esophageal squamous cell carcinoma.Int J Oncol, 1998,13(3) :455-460.
  • 8Anayama T, Furihata M, Ishikawa T, et al. Positive correlation between p27Kip1 expression and progression of human esophageal squamous cell carcinoma. Iht J Cancer, 1998,79(4):439-443.
  • 9Nozoe T, Korenaga D, Futatsugi M, et al. CyclinA expression in superficial squamous cell carcinoma of the esophagus and coexisting infiltrate lymphocyte follicle. Cancer Lett, 2002, 188 (1-2):221-229.
  • 10Nozoe T,Korenaga D,Kabashima A,et al. Significance of cyclinB1 expression as an independent prognostic indicator of patients with squamous cell carcinoma of the esophagus. Clin Cancer Res,2002,8(3) :817-822.

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国外医学（肿瘤学分册）
2004年 第6期

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