期刊文献+

HER2过度表达乳腺癌的辅助治疗研究进展 被引量:1

下载PDF
导出
摘要 HER2基因与乳腺癌的发生发展及转移有密切关系 ,HER2过度表达与化疗、内分泌治疗抵抗有关 ,进一步的标准化检测及分析方法将对HER2在肿瘤中深入研究起到推动作用。
出处 《临床外科杂志》 2004年第6期370-371,共2页 Journal of Clinical Surgery
  • 相关文献

参考文献15

  • 1Spiridon CI,Ghetie,MA Uhr J,et al.Targeting multiple Her-2 epitopes with monoclonal antibodies results in improved antigrowth activity of a human breast cancer cell line in vitro and in vivo[J].Clinical Cancer Research,2002,8∶1720-1730.
  • 2Lobleigh MA,Vogel CL,Tripathy D,et al.Multinational study of the efficacy and safety o humanized anti-HER2monoclonal antibody in women who have HER2-overexpression metastatic breast cancer that has progressed after chemotherapy for metastatic disease[J].J
  • 3Wentao Yang,Kristina Klos,Ying Yang,et al.ErbB2 overexpression correlates with increased expression of vascular endothelial growth factors A,C, and D in breast carcinoma[J].Cancer,2002,94:2855-2861.
  • 4Slamon DJ,Leyland Jones B,Shak S,et al.Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2[J].N Engl J med,2001,344(11):783-792.
  • 5Bunone G,Briand PA,Miksicek RJ,et al.Activation of the unliganded estrogen receptor by EGF involves the MAPKinase pathway and direct phosphorylation[J].EMBO J,1996,15:2174-2183.
  • 6SJ Houston,TA Plunkett,DM Barnes,et al.Overexpression of c-cerbB2 is an independent marker of resistance to endocrine therapy in advanced breast cancer[J].British Journal of Cancer,1999,79:1260-1269.
  • 7Lipton A,Ali SM,Leitael K,et al.Elevated serum HER2/neu level predicts decreased response to hormone therapy in metastatic breast cancer[J].Journal of Clinical Oncology,2002,20:1467-1472.
  • 8Berry DA,Muss HB,Thor AD,et al.HER2/neu and P53 expression versus tamoxifen resistance in estrogen receptor-positive,node-positive breast cancer[J] Journal of Clinical Ocology,2000,18:3471-3479.
  • 9Dowsett M,Harper-Wynne I,Boeddinghaus I,et al.Significant antiproliferative effects of endocrine therapy in ER+HER+breast Carcinomas[J].Eur J cancer,2000,36:S120-S121.
  • 10Sylvie Menard,Andrea balsari,Patrizia Casalini,et al.HER2-positive breast carcinomas as a particular subset with peculiar clinical behaviors[J].Clinical Cancer Research,2002,8:520-525.

同被引文献7

引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部