超高效液相色谱–质谱法测定动物源食品中硝基呋喃类代谢物残留量的方法验证

Method Validation of Determination of Nitrofuran Metabolites in Animal Derived Food by Ultra High Performance Liquid Chromatography-Mass Spectrometry

为提高检测能力,本实验室验证了农业部781号公告-4-2006《动物源食品中硝基呋喃代谢物残留量的测定,高效液相色谱法–串联质谱法》的适用性。本方法验证主要从适用范围、标准曲线、线性、灵敏度、精密度及回收率进行,通过试验发现,本实验室的适用范围标准曲线、线性、灵敏度、精密度及回收率均满足该标准的要求,可以利用该标准对外开展检测业务。

To improve detection capability,the laboratory verified the applicability of Ministry of Agriculture Notice No.781-4-2006 Determination of nitrofuran metabolites in animal derived food by high performance liquid chromatography-tandem mass spectrometry.This method is mainly verified from the test coverage,standard curve,linearity,sensitivity,precision and recovery rate.Through the test,it is found that the standard curve,linearity,sensitivity,precision and recovery rate of the applicable range meet the requirements of the standard.The standard can be used to conduct ex-ternal testing operations.