骨髓增殖性肿瘤症状管理现状

The Symptom Management of Myeloproliferative Neoplasms

骨髓增殖性肿瘤(MPN)是来源于克隆性造血干细胞的恶性肿瘤,包括真性红细胞增多症(PV)、原发性血小板增多症(ET)和骨髓纤维化(MF)。MPN患者存在疲劳、头痛、恶心、盗汗、瘙痒等不适症状,严重降低患者生活质量。近年来,研究重点转向对患者自我感知不适症状了解及控制上,本文介绍了MPN症状负荷及相关症状管理工具,突出中医药治疗MPN优势。

Myeloproliferative neoplasms (MPN) are clonal hematopoietic stem cell-derived malignancies that include polycythemia vera (PV), essential thrombocythemia (ET) and myelofibrosis (MF). Symptoms experienced by MPN patients are fatigue, headache, nausea, night sweats, itching and so on, and these symptoms seriously reduce the quality of life, which in the group of this disease. In recent years, researchers pay attention to the self perceived symptom of MPN patients, and focus on the understanding and management towards these symptoms. This paper introduces the symptom burden of MPN and Symptom Assessment Tools, and emphasises on the advantage of Chinese medicine in the treatment of MPN.