浅谈真实世界研究及其在中医药领域的应用

Real World Study and Its Application in the Field of Traditional Chinese Medicine

循证医学可以说是医学研究领域中的一场革命,不可否认的是,其研究所得出来的结论具有很高的可靠性,这也是它显著优于经验性研究的一大优势。尤其是多中心大样本的随机对照试验,很长一段时间受到了广大医学研究者的青睐。在临床中也广泛应用循证医学所得出的结论作为指导依据。近年来,循证医学逐步深入发展,但由于其方法学上的局限性,其优势在临床中并未得到充分发挥,一些来自随机对照试验(RCT, Randomized Controlled Trial)的高级别临床证据缺乏临床实际应用价值。越来越多的研究者把注意力投向了真实世界研究(RWS, Real World Study),现将真实世界研究方法做简要介绍。

Evidence-based medicine can be said to be a revolution in the field of medical research. It is unde-niable that the conclusions obtained by evidence-based medicine have a high reliability, which is also a great advantage of Evidence-Based Medicine (EBM), which is significantly superior to em-pirical research. In particular, randomized controlled trials with large multicenter samples have been favored by many medical researchers for a long time. Evidence-based medicine is also widely used as a guide in clinical practice. In recent years, evidence-based medicine (EBM) has been de-veloped gradually, but because of its methodological limitations, its advantages have not been brought into full play in clinical practice. Some high-grade clinical evidence from randomized con-trolled trial (RCT, Randomized Controlled Trial) lacks practical clinical value. More and more re-searchers have turned their attention to real-world research (RWS, Real World Study). Now this article briefly introduces real-world research methods.