肺癌治疗的现状与进展

Present Situation and Progress of Lung Cancer Therapy

肺癌发病率成逐年递增趋势,是临床最常见的恶性肿瘤, 治疗方法包括手术、化疗、放疗、分子靶向治疗、免疫治疗等。手术、化疗、放疗是肺癌主要治疗手段,但是临床适宜手术治疗的病人只有20%~30%,传统化疗方案疗效有限,5年生存率仍小于15%,放疗副作用较大,故限制了其应用。目前,以分子靶向治疗、免疫治疗、放射性碘125粒子立体植入等多学科综合治疗为代表的新治疗方法,丰富了肺癌治疗的手段,该文综述了目前肺癌治疗现状及最新发展趋势。

The lung cancer incidence is increasing year by year, and it is the most common malignant tumor in clinic. Treatment includes surgery, chemotherapy, radiotherapy, molecular targeted therapy, immunotherapy, and so on. Surgery, chemotherapy and radiotherapy are the main treatments for lung cancer. However, only 20% to 30% patients are clinically suitable for surgical treatment. The traditional chemotherapy regiment has limited efficacy. The 5-year survival rate is still less than 15%, and the side effects of radiotherapy are relatively large. At present, the new treatment methods, such as molecular targeted therapy, immunotherapy, iodine 125 seed stereotherapy and so on, have enriched the treatment of lung cancer. This article reviews the current treatment status and the latest development trend of lung cancer.