偏头痛发病机制和镁缺乏

Pathogenesis of Migraine and Magnesium Deficiency

偏头痛是一种临床常见慢性反复发作的致残性神经血管性疾病,给患者、家庭和社会均带来沉重的经济负担。近年来越来越多学者研究发现偏头痛患者血清镁离子下降,给予镁剂能缓解部分偏头痛患者的症状,由此推测镁缺乏与偏头痛发作有密切关系。本文基于此对镁缺乏和偏头痛发病机制的国内外研究文献进行综述,对镁剂在偏头痛发病机制中的作用进行总结,为偏头痛的防治展开新的方向。

The migraine is a kind of disabling neurovascular disease that is common in the clinical practice of chronic recurrence, which brings a heavy economic burden on patients, family and society. In recent years, more and more scholars have found that the serum magnesium ion in migraine pa-tients has decreased, and the administration of magnesium can alleviate the symptoms of some migraine patients. Therefore, magnesium deficiency is closely related to migraine attack. Based on the review of the domestic and foreign literature on the pathogenesis of migraine and magnesium deficiency, this paper summarizes the role of magnesium in the pathogenesis of migraine, and develops a new direction for the prevention and treatment of migraine.