肿瘤心脏病学及老年肿瘤患者抗肿瘤治疗相关心血管毒性研究进展

Advances in the Study of Cardio-Oncology and Cardiovascular Toxicity Related to Tumor Cardiology in Elderly Cancer Patients

随着人口老龄化、生活方式及饮食习惯不断改变,近年来肿瘤发病率呈逐渐增高趋势,同时随着医疗技术不断进步,癌症治疗水平不断提高,使得肿瘤患者的治愈率不断提高,患者生存时间和生活质量均得到显著提高。但是无论现有的和新兴的癌症治疗方法都会对患者的心血管系统产生毒性作用,从而影响其心血管健康,进而引起患者原有心脏病恶化或心法心血管事件,导致肿瘤患者长期发病率和死亡率明显增加,日益成为影响这类疾病预后的关键因素。对于此类患者在保证患者最有效的癌症治疗的同时,促进患者的心血管健康,最大限度降低抗肿瘤治疗心血管毒性、保护心血管系统功能,是未来研究及发展方向。

With the aging of the population and the changes of lifestyle and eating habits in recent years, the incidence of cancer increased gradually, at the same time as medical technology continues to progress, and constantly improve the level of treatment of cancer, the tumor cure rate of patients with increasing survival time and quality of life are improved significantly. But both existing and emerging cancer treatment will produce toxic effects on the cardiovascular system, thus affecting the cardiovascular health, and patients with heart disease caused by the original deterioration or heart cardiovascular events, resulting in long-term morbidity and mortality of cancer patients in-creased significantly, has increasingly become the key factors affecting the prognosis of the disease. For such patients, while ensuring the most effective cancer treatment for patients, it is also the direction of future research and development to promote cardiovascular health of patients, minimize cardiovascular toxicity and protect cardiovascular system function.