强脉冲光治疗睑板腺功能障碍的安全性与有效性

Safety and Efficacy of Intense Pulsed Light in the Treatment of Meibomian Gland Dysfunction

目前强脉冲光(intense pulsed light, IPL)在眼科领域中的应用逐渐兴起,因其具有无创、简单、安全、效果好等优点。IPL可抑制炎症介质,并促进睑脂排出,减少皮肤表面细菌和螨虫数量,增加泪膜的稳定性,使泪膜水液层的蒸发降低,因此其可以改变干眼患者的症状和体征。通过国内外报道指出,IPL在治疗睑板腺功能障碍(meibomian gland dysfunction, MGD)方面有一定的价值,其疗效显著优于单纯睑板腺按摩及药物治疗,并且其在眼科应用的安全性较高。本文阐述了IPL治疗MGD的安全性及有效性,对未来的发展进行了展望。

At present, the application of intense pulsed light (IPL) in the field of ophthalmology is gradually emerging, because of its advantages of non-invasive, simple, safe and good effect. IPL can inhibit inflammatory mediators, promote palpebral sebum excretion, reduce the number of bacteria and mites on the skin surface, increase the stability of tear film, reduce evaporation of tear film aqueous layer, so it can change the symptoms and signs of patients with dry eyes. According to domestic and foreign reports, IPL has certain value in treating meibomian gland dysfunction (MGD), and its curative effect is significantly better than simple meibomian gland massage and drug therapy. And the safety of its application in ophthalmology is higher. This paper describes the safety and effectiveness of IPL treating MGD, and prospects the future development.