联合普萘洛尔治疗高风险婴幼儿皮肤血管瘤并溃疡临床疗效观察

Clinical Efficacy of Many Ways Combined with Propranolol in the Treatment of High Risk Infants with Skin Hemangioma and Ulcer

目的:探讨联合普萘洛尔多种方法治疗高风险婴幼儿皮肤血管瘤并溃疡的临床疗效。方法:口服β-受体阻滞剂普萘洛尔,联合含银敷料、人工皮亲水性敷料、自制抗炎洗剂、红外线照射、冻干重组人酸性成纤维细胞生长因子喷剂等治疗。结果:6个月时瘤体消退有效率达80%,溃疡愈合率达100%。结论:对于高风险婴幼儿皮肤血管瘤合并溃疡患者,采用口服普萘洛尔联合多种治疗方法,疗效明显,不良反应小,可作为严重婴幼儿血管瘤的治疗方法之一。

Objective: To investigate the clinical efficacy of many ways combined with propranolol in the treatment of high-risk infantile skin hemangioma with ulcer. Methods: Propranolol, a β-receptor blocker, was given orally, combined with silver dressing, hydrophilic dressing of artificial skin, self-made anti-inflammatory lotion, infrared radiation, lyophilized recombinant human acidic fibroblast growth factor spray. Results: After 6 months, the effective rate of tumor regression was 80%, and the ulcer healing rate was 100%. Conclusion: For patients with high-risk infantile skin hemangioma complicated with ulcer, oral propranolol combined with a variety of treatment methods has obvious curative effect and little adverse reaction, which can be used as one of the treatment methods for severe infantile hemangioma.