糖尿病影响冻结肩发生的相关机制研究

Study on the Mechanism about the Effect of Diabetes Mellitus on the Occurrence of Frozen Shoulder

随着人口老龄化进程的不断加快,冻结肩的患病率逐年升高,其中很大一部分患者同时伴有糖尿病。伴有糖尿病冻结肩的发生往往症状严重,治疗预后效果比较差,成为临床医师的一大挑战。本文通过回顾文献,从糖尿病患者冻结肩的高患病率及糖尿病微循环障碍、促炎症纤维化因子、血管内皮生长因子、糖基化终末产物几个方面,探讨了糖尿病患者影响冻结肩发生的相关机制,以提高糖尿病患者冻结肩的管理效果和新治疗方法的开发研究。

With the continuous acceleration of the aging process of the population, the prevalence rate of frozen shoulder is increasing year by year, and a large number of patients are accompanied by diabetes. The occurrence of frozen shoulder with diabetes often has serious symptoms and poor prognosis, which has become a major challenge for clinicians. In this paper, we discussed the related mechanisms of diabetic patients affecting the occurrence of frozen shoulder by reviewing the literature, from the aspects of high prevalence rate of frozen shoulder in diabetic patients, diabetes microcirculation disturbance, pro-inflammatory fibrosis factor, vascular endothelial growth factor and advanced glycation end products, in order to improve the management effect of frozen shoulder in diabetic patients and find new treatment methods.