近视病因与发病机制的研究进展

Research Progress on Etiology and Pathogenesis of Myopia

近视已成为全球性的问题,尤其在东亚和东南亚的城市地区普遍,近视不仅增加患者的经济,更重要的是其相关的眼部并发症如白内障、青光眼及黄斑病变等可能导致患者视力严重下降甚至失明。近些年来关于对近视发病机制的研究已逐渐聚焦于分子生物学水平,人们开始从更深层次探索近视发病的原因,为研究近视防控提供潜在治疗靶点。

Myopia has become a global problem, especially in urban areas of East Asia and Southeast Asia. Myopia not only increases the patient’s economy, but also, more importantly, its related ocular complications such as cataract, glaucoma and macular degeneration may lead to severe vision loss or even blindness. In recent years, the research on the pathogenesis of myopia has gradually focused on the level of molecular biology. People have begun to explore the causes of myopia from a deeper level to provide potential therapeutic targets for the prevention and control of myopia.