系统性红斑狼疮生存率及相关影响因素的研究进展

Research Progress of Systemic Lupus Erythematosus Survival Rate and Related Influencing Factors

近几十年来,随着临床诊治水平的提高,以及有关生存因素的研究,系统性红斑狼疮(systemic lupus erythematosus, SLE)患者的预后有了很大的改善。国内外对SLE生存率及相关因素的研究表明:感染、脏器损害(肾脏,中枢神经系统,心血管系统为主要原因)、治疗方式的选择与应用、以及妊娠、心理、性别、年龄、种族、社会经济文化状况等都对SLE的生存率产生一定的影响。

The prognosis for patients with systemic Lupus erythematosus (SLE) has improved greatly in recent decades, thanks to improved clinical diagnosis and treatment as well as studies on survival factors. Studies on SLE survival rate and related factors at home and abroad have shown that infection, organ damage (kidney, central nervous system and cardiovascular system are the main causes), selection and application of treatment, pregnancy, psychology, gender, age, race, socioeconomic and cultural status all have certain influences on SLE survival rate.