不完全川崎病的诊断和治疗

Diagnosis and Treatment of Incomplete Kawasaki Disease

川崎病(Kawasaki disease, KD)又称皮肤黏膜淋巴结综合征,是一种病因不明,以免疫系统活化和血管内皮系统广泛损害为特征的急性自限性疾病。目前由于KD缺乏特异性实验室诊断以及特异性病理学特征,因此其诊断依赖于临床诊断标准的判定。不完全川崎病(Incomplete Kawasaki disease, IKD)因临床表现不完全,容易被漏诊或误诊,未及时给予有效治疗,从而增加冠状动脉病变(Coronary artery lesions, CAL)的发生率。本文就不完全川崎病的诊断和治疗进行综述。

Kawasaki disease (KD), also known as mucocutaneous lymph node syndrome (MCLS), is an acute self-limited disease with unknown etiology and characterized by immune system activation and extensive damage to the vascular endothelial system. At present, due to the lack of specific laboratory diagnosis and specific pathological features of KD, its diagnosis relies on the determination of clinical diagnostic criteria. Due to its incomplete clinical manifestations, incomplete Kawasaki disease (IKD) is easy to be missed or misdiagnosed, and not timely given effective treatment, thus increasing the incidence of coronary artery lesions (CAL). This article reviews the diagnosis and treatment of incomplete Kawasaki disease.