轻微型肝性脑病的诊断方法研究进展

Research Progress in the Diagnosis of Minimal Hepatic Encephalopathy

轻微型肝性脑病(minimal hepatic encephalopathy, MHE)是肝性脑病发病过程中的一个早期阶段,隐匿性强,仅能通过特殊的神经心理学测试或神经生理学检查才能识别出来,临床漏诊率高。MHE会影响患者与健康相关的生活质量、驾驶能力、社会经济地位等方面,因此,早期诊断MHE并及时给予患者有效的临床干预至关重要。MHE的诊断方法有很多,主要包括神经心理学测试、神经生理学检查和影像学检查,现就国内外MHE的诊断方法研究进展作一综述,从而提高对不同诊断方法的认识。

Minimal hepatic encephalopathy (MHE) is an early stage in the pathogenesis of hepatic encephalopathy. It is highly concealed and can only be identified through special neuropsychological tests or neurophysiological examinations, and the rate of clinical missed diagnosis is high. MHE can affect the health related quality of life, driving ability, socioeconomic status and other aspects of patients. Therefore, it is very important to diagnose MHE early and give patients effective clinical intervention in time. There are many diagnostic methods for MHE, mainly including neuropsychological tests, neurophysiological examinations and imaging examinations. This article reviews the research progress of domestic and abroad MHE diagnostic methods, so as to improve the understanding of different diagnostic methods.