摘要
目的:提高临床医师对秋水仙碱中毒导致急性肾损伤的发生机制、临床表现及治疗措施的认识。方法:我们对青岛大学附属医院收治的1例秋水仙碱中毒致急性肾损伤患者的临床资料进行回顾性分析,并且复习相关文献。结果:给予连续肾脏替代疗法(Continuous Renal Replacement Therapy, CRRT)、血浆置换、成分输血、刺激骨髓造血、抗感染、纠正电解质紊乱、营养心肌等一系列对症支持治疗后好转出院。结论:秋水仙碱大剂量服用可出现严重急性肾损伤,早期进行积极对症处理,可提高患者存活率和减少并发症的发生。
Objective: To improve the understanding of the pathogenesis, clinical manifestation and treatment of acute kidney injury caused by colchicine poisoning. Methods: We retrospectively analyzed the clinical data of a patient with acute kidney injury caused by colchicine poisoning in the Affiliated Hospital of Qingdao University, and reviewed relevant literature. Results: The patient was given a series of symptomatic supportive treatments, such as plasma exchange, continuous renal replacement therapy, component transfusion, anti-infective therapy, and myocardial nutrition, and then she was improved and discharged. Conclusion: Large-dose colchicine can cause severe acute kidney injury. Early symptomatic treatment can improve the survival rate of patients and reduce the incidence of complications.
出处
《临床医学进展》
2021年第4期1920-1924,共5页
Advances in Clinical Medicine
