三种血清蛋白因子在结直肠癌早期诊断中的意义

Significance of Three Serum Protein Factors in Early Diagnosis of Colorectal Carcinoma

近年来,结直肠癌逐渐成为我国肿瘤疾病死亡的主要原因之一,尽管结直肠癌的诊断和预后方面不断进展,但早期检测筛查方法仍需改进,还需确定新的生物标志物。目前较多研究发现乳铁蛋白、环氧化酶-2、内皮细胞特异性分子-1与结直肠癌的发生、发展密切相关,本文就其三种蛋白因子在结直肠癌中的表达及意义作一探讨。

For the past few years, colorectal cancer has gradually become one of the leading causes of cancer-related death in China. Despite continued progress in the diagnosis and prognosis of colorectal cancer, early detection and screening methods still need to be improved, new biomarkers need to be identified. At present, many studies have found that lactoferrin, COX-2 and endothelium specific molecule-1 are closely related to the occurrence and development of colorectal cancer. This article will discuss the expression and significance of lactoferrin, COX-2 and endothelial specific molecule-1 in colorectal cancer.