摘要
目的:评价参麦注射液治疗气阴两虚型慢性心力衰竭的临床效果。方法:慢性心力衰竭患者60例采用随机数字表法随机分为两组,对照组采用常规西药治疗,试验组在对照组用药基础上加用参麦注射液,干预治疗4周,对治疗后两组心功能疗效、临床症状及LVEF、NT-proBNP、6MWD水平改善情况进行比较。结果:试验组有效率93.10%,对照组有效率75.86%,两组疗效差异有统计学意义(P 【0.05);两组中医证候积分治疗后均较治疗前明显改善,差异有统计学意义(P 【0.05)。试验组的改善程度优于对照组,差异有统计学意义(P 【0.05);且两组患者治疗后,LVEF、NT-proBNP、6MWD水平较前明显改善(P 【0.05),且试验组改善程度优于对照组,差异具有统计学意义(P 【0.05)。结论:参麦注射液治疗气阴两虚型慢性心力衰竭疗效确切,值得推广。
Objective: To evaluate the clinical effect of Shenmai injection in the treatment of chronic heart failure with deficiency of both qi and yin. Method: 60 patients with chronic heart failure were randomly divided into two groups by random number table method. The control group was treated with conventional western medicine, and the experimental group was treated with Shenmai injection on the basis of the control group. Intervention treatment was performed for 4 weeks. The efficacy of cardiac function, clinical symptoms and the improvement of LVEF, NT-proBNP and 6MWD levels were compared between the two groups. Results: The effective rate of the experimental group was 93.10%, and the effective rate of the control group was 75.86%. The difference in efficacy between the two groups was statistically significant (P <0.05);the scores of TCM syndromes in the two groups were significantly improved after treatment compared with before treatment, and the difference was statistically significant (P <0.05). The improvement of the test group was better than that of the control group, and the difference was statistically significant (P <0.05);and after treatment, the levels of LVEF, NT-proBNP, and 6MWD in the two groups were significantly improved (P <0.05), and the improvement degree of the test group was better than that of the control group, and the difference was statistically significant (P <0.05). Conclusion: Shenmai injection is effective in treating chronic heart failure with deficiency of both qi and yin, and it is worthy of promotion.
出处
《临床医学进展》
2021年第10期4699-4704,共6页
Advances in Clinical Medicine
