TG/HDL比值与缺血性脑血管病患者颈动脉粥样硬化狭窄的相关性研究

Correlation between TG/HDL Ratio and Carotid Atherosclerotic Stenosis in Patients with Ischemic Cerebrovascular Disease

目的:探讨缺血性脑血管病患者TG/HDL比值与患者颈动脉粥样硬化狭窄之间的关系。方法:回顾性分析167例经头颈CT或MR确诊缺血性脑血管病患者的临床资料,均行头颈动脉CT血管成像(CTA)检查,依据CTA结果分为有颈动脉粥样硬化狭窄组103例,无颈动脉粥样硬化狭窄组64例。同时采集患者临床生化指标,比较患者临床生化指标及TG/HDL比值与缺血性脑血管病患者颈动脉狭窄之间的关系。结果:与无颈动脉粥样硬化狭窄患者比较,颈动脉粥样硬化狭窄组患者TG/HDL水平明显升高(P 【0.05),TG,TG/HDL对预测缺血性脑血管病颈动脉粥样硬化狭窄中的ROC曲线下面积分别为0.7402,0.7602,(P 【0.05),TG/HDL评分准确性更高。结论:在缺血性脑血管病患者中TG,TG/HDL是评估颈动脉粥样硬化狭窄的客观指标,且TG/HDL准确性更高。

Objective: To investigate the relationship between TG/HDL ratio and carotid atherosclerotic stenosis in patients with ischemic cerebrovascular disease. Methods: The clinical data of 167 patients with ischemic cerebrovascular disease diagnosed by head and neck CT or MR were analyzed retrospectively. All patients underwent head and neck CT angiography (CTA). According to the CTA results, they were divided into 103 cases with carotid atherosclerosis stenosis group and 64 cases without carotid atherosclerosis stenosis group. At the same time, the clinical biochemical indexes were collected to compare the relationship between clinical biochemical indexes, TG/HDL ratio and carotid stenosis in patients with ischemic cerebrovascular disease. Results: Compared with patients without carotid atherosclerotic stenosis, the levels of TG and HDL in the carotid atherosclerotic stenosis group were significantly higher (P <0.05). The areas under the ROC curve of TG and TG/HDL in predicting carotid atherosclerotic stenosis of ischemic cerebrovascular disease were 0.7402 and 0.7602 respectively (P <0.05). The accuracy of TG/HDL score was higher. Conclusion: TG and TG/HDL are objective indexes to evaluate carotid atherosclerotic stenosis in patients with ischemic cerebrovascular disease, and the accuracy of TG/HDL is higher.