摘要
乙型病毒性肝炎的发展与免疫系统密切相关,患者确诊慢性乙型病毒性肝炎(CHB)后,体内乙型肝炎病毒(HBV)与多种免疫细胞及免疫因子相互作用,继而影响机体的免疫状态及治疗效果,这个过程可持续数十年,最终对患者造成不同的临床结局。其中CD4+T细胞及CD8+T细胞对HBV感染者免疫状态的影响已被众多研究者认可,但临床医师依然忽略了它的检测价值,因此详述其在CHB病程中的变化及作用对推广其在临床上的应用是尤为重要的。
The development of viral hepatitis B is closely related to the immune system. After patients are diagnosed with chronic viral hepatitis B, HBV interacts with a variety of immune cells and immune factors, and then affects the immune state and treatment effect of the body. This process can last for decades, and finally leads to different clinical outcomes for patients. The effects of CD4+T cells and CD8+T cells on the immune status of HBV infected persons have been recognized by many researchers, but clinicians still ignore its detection value. Therefore, it is particularly important to detail the changes and effects in the course of CHB disease to promote its clinical application.
出处
《临床医学进展》
2021年第11期5386-5390,共5页
Advances in Clinical Medicine
