摘要
心房颤动作为一种最常见的心律失常之一,其中持续性心房颤动对心脏结构及心肌纤维化方面的作用最为显著。而沙库巴曲缬沙坦的问世对于心房颤动所引起的心脏结构及心肌纤维化的改变有一定的影响,在治疗心房颤动方面提供了新的治疗方案及进展,因此本文将对持续性心房颤动的发病机制、沙库巴曲缬沙坦药理机制及沙库巴曲缬沙坦钠在持续性心房颤动患者的心脏结构及心肌纤维化指标的影响进行综述。
Atrial fibrillation is one of the most common arrhythmias, in which persistent atrial fibrillation has the most significant effect on cardiac structure and myocardial fibrosis. The advent of sacubitril valsartan sodium hydrate has a certain impact on the changes of cardiac structure and myocardial fibrosis caused by atrial fibrillation, and provides a new treatment scheme and progress in the treatment of atrial fibrillation. Therefore, this paper will study the pathogenesis of persistent atrial fibrillation and reviews the pharmacological mechanism of sacubitril valsartan sodium hydrateand the effects of sacubitril valsartan sodium hydrate on cardiac structure and myocardial fibrosis in patients with persistent atrial fibrillation.
出处
《临床医学进展》
2021年第12期6123-6128,共6页
Advances in Clinical Medicine
