色素沉着绒毛结节性滑膜炎调强放疗2例

Two Cases of Pigmented Villous Nodular Synovitis Treated with Intensity-Modulated Radiotherapy

目的:通过对2例色素沉着绒毛结节性滑膜(Pigmented villonodular synovitis, PVNS)病的学习,为临床治疗开拓思路。方法:本研究通过对本院诊断的2例PVNS病例行回顾分析并随访,结果:患者经治疗后随访目前活动自如无复发。结论:PVNS是一种良性但侵袭性的肿瘤性炎症性疾病,预后差,通常累及大关节以及腱鞘,早期表现无明显特征容易漏诊,易致残,放射治疗(Radiation therapy)作为术后的辅助治疗更好地弥补了手术无法全切及术后手术边缘为阳性的DPVN患者,降低复发率,缓解病情。

Objective: By studying 2 cases of pigmented villonodular synovitis (PVNS) disease, to develop ideas for clinical treatment. Methods: In this study, two cases of PVNS diagnosed in our hospital were retrospectively analyzed and followed up. Results: The patients are now moving freely without recurrence after treatment and follow-up. Conclusion: PVNS is a benign but aggressive neoplastic inflammatory disease with poor prognosis, usually involving large joints and tendon sheaths, and the early manifestations have no obvious features and are easily missed. Radiation therapy, as an auxiliary treatment after surgery, can better compensate for patients with DPVN that cannot be completely removed or whose postoperative surgical edge is positive, thus reducing the recurrence rate and alleviating the condition.