微生物群在乳腺癌中的研究进展

Research Progress of Microbiome in Breast Cancer

乳腺癌是女性癌症相关死亡的重要原因且病因不明,少数与遗传易感性有关,多数为散发,散发性病例的病因是癌症研究的一个重要领域。越来越多的研究显示微生物群失调与乳腺癌发生发展相关,本文对乳腺癌患者乳腺皮肤、乳腺组织、乳汁和肠道中发现的微生物及其对治疗的影响进行综述,对乳腺癌与微生物群的关系进行初步探索。

Breast cancer is a significant cause of cancer-related death in women and its etiology is unknown. A small number of patients are associated with genetic susceptibility and most are disseminated. The cause of sporadic cases is an important area of cancer research. A growing number of studies have shown that microbiota dysbiosis is associated with the development of breast cancer. This article provides a review of the microbiota found in the breast skin, breast tissue, milk and intestine of breast cancer patients and its impact on treatment, with the aim of providing a preliminary exploration of the relationship between breast cancer and the microbiota.