马方综合征和原发性醛固酮增多症,巧合还是存在某种联系?病例报告

Marfan Syndrome and Primary Hyperaldosteronism, Coincidence or There Is Some Kind of Connection? Case Reports

原发性醛固酮增多症(PA,简称原醛症)常可引起难以控制的高血压。随着诊疗技术的不断进展,近年来发现其患病率逐渐上升,但临床也常有漏诊误诊的情况。马方综合征(Marfan syndrome, MFS)是一种罕见的常染色体显性遗传性疾病,全身系统均可累积,但主要累积心血管系统导致患者发生不可预知的死亡。原醛症合并马方综合征病例罕见,本文结合文献报道1例因怀疑原醛症入院后确诊MFS病例及相关文献复习,并讨论了两种病变之间的可能联系。

Primary hyperaldosteronism (PA) can often cause uncontrollable hypertension. With the continu-ous progress of diagnosis and treatment technology, in recent years, it has been found that its prev-alence has gradually increased, but there are often cases of missed diagnosis and misdiagnosis in clinical practice. Marfan syndrome (MFS) is a rare autosomal dominant disorder that accumulates throughout the system, but predominantly accumulates the cardiovascular system that causes un-predictable death in patients. Cases of primary hyperaldosteronism complicated with marfan syn-drome are rare, and this paper reports a confirmed MFS case after admission to hospital with sus-pected primary hyperaldosteronism and a review of the relevant literature, and discusses the pos-sible link between the two lesions.