不同程度海拔对藏、汉族OSAHS患者肝功能影响研究进展

Research Progress on Effects of Different Altitude on Liver Function of Tibetan and Han OSAHS Patients

阻塞性睡眠呼吸暂停低通气综合征(OSAHS)是由多种原因导致睡眠状态下反复出现低通气和(或)呼吸中断,引起慢性间歇性低氧血症伴高碳酸血症以及睡眠结构紊乱,进而使机体发生一系列病理生理改变的临床综合征。研究发现,OSAHS的病情严重程度与海拔高度和不同民族等有关,不同海拔不同民族患者的肝功能也会有差异,因此,本文就此种差异做一综述,对不同OSAHS患者将来的诊治提供思路。

Obstructive sleep apnea hypopnea syndrome (OSAHS) is a clinical syndrome of chronic intermittent hypoxemia accompanied by hypercapnia and sleep structure disorder caused by repeated hypop-nea and/or respiratory interruption during sleep due to various reasons, and then a series of path-ophysiological changes occur in the body. Studies have found that the severity of OSAHS is related to altitude and different ethnic groups, and patients with different altitude and different ethnic groups also have different liver functions. Therefore, this paper summarizes these differences and provides ideas for future diagnosis and treatment of different OSAHS patients.