晚期黑色素瘤的治疗进展综述

Progress in the Treatment of Advanced Melanoma

黑色素瘤是世界上致命的癌症,晚期黑色素瘤恶性程度较高,由于发病比较隐匿,绝大多数病人诊断恶性黑色素瘤时疾病往往已经进入中晚期;黑色素瘤进入中晚期后治疗难度加大,手术切除及化疗的预后通常很差,随着对黑色素瘤不断深入地研究,在传统手术及化疗的基础上,出现了许多新的治疗方法,包括免疫治疗、靶向治疗及联合治疗等,本文对晚期黑色素瘤治疗的研究进展作一综述。

Melanoma is a fatal cancer in the world. Advanced melanoma has a high degree of malignancy. Due to the hidden incidence, most patients often enter the middle and advanced stage when they diag-nose malignant melanoma;after melanoma enters the middle and advanced stage, the treatment becomes more difficult, and the prognosis of surgical resection and chemotherapy is usually very poor. With the continuous in-depth research on melanoma, many new treatment methods have emerged on the basis of traditional surgery and chemotherapy, including immunotherapy, targeted therapy and combined therapy. This paper summarizes the research progress of the treatment of advanced melanoma.