摘要
目的:探讨利用磁共振q-Dixon技术鉴别脊柱血管瘤和脊柱常见恶性肿瘤的价值。材料和方法:收集自2021年1月至2021年8月经病理证实或经长期随访证实的脊柱血管瘤和脊柱常见恶性肿瘤各30例。所有患者均行常规MRI检查及q-Dixon检查,扫描数据上传至Siemens syngo.via工作站,经后处理获得FF图(脂肪分数图)。在FF图上勾画感兴趣区(Region of interest, ROI)得到FF值,对符合正态分布的数据以平均值 ±标准差表示,使用独立样本t检验分析两组间脂肪含量差异的统计学意义。利用受试者工作特性曲线(Receiver operating characteristic curve, ROC曲线)分析其诊断效能。结果:脊柱恶性肿瘤FF值为(11.55 ±7.31)%,脊柱血管瘤FF值为(58.6 ±15.70)%。脊柱恶性肿瘤的FF值小于血管瘤的FF值,两组数值间的差异具有统计学意义(t = 14.90, P < 0.001),绘制FF值对脊柱血管瘤和脊柱常见恶性肿瘤鉴别诊断效能的ROC曲线,AUC为1.00,敏感度和特异度为100%,鉴别脊柱血管瘤和恶性肿瘤的FF值的临界值为25.0%。结论:磁共振q-Dixon技术对鉴别脊柱血管瘤和脊柱常见恶性肿瘤具有良好的诊断价值。
Purpose: To evaluate the value of q-Dixon technique in distinguishing spinal hemangioma from spinal malignancy. Materials and methods: A total of 30 cases of spinal hemangioma and common malignant tumors of the spine proved by pathology or clinical follow up were collected from January 2021 to August 2021. All patients underwent conventional MRI and q-Dixon examination. The scan data were uploaded to Siemens syngo.via workstation and FF map (fat fraction map) was obtained after post-processing. The region of interest (ROI) was delineated on the FF map to obtain FF values, and the data with normal distribution were expressed as mean ±standard deviation. The inde-pendent sample T test was used to analyze the statistical significance of fat content differences be-tween the two groups. Receiver operating characteristic curve (ROC curve) was used to analyze its diagnostic efficiency. Results: The FF value of spinal malignant tumor was (11.55 ±7.31)% and that of spinal hemangioma was (58.6 ±15.70)%. The FF value of spinal malignancies was smaller than that of hemangiomas, and the difference between the two groups was statistically significant (t = 14.90, P < 0.001), the ROC curve of FF value for differential diagnosis of spinal hemangioma and common spinal malignant tumor was drawn. The area under the curve (AUC) was 1.00, the sensitiv-ity and specificity were 100%, and the critical value for differential diagnosis of spinal hemangioma and malignant tumor was 25.0%. Conclusion: MRI q-Dixon technique has good diagnostic value in distinguishing spinal hemangioma from common spinal malignancies.
出处
《临床医学进展》
2022年第7期6026-6032,共7页
Advances in Clinical Medicine