减瘤性肾切除在转移性肾细胞癌治疗中的地位

The Role of Cytoreductive Nephrectomy in the Treatment of Metastatic Renal Cell Carcinoma

减瘤性肾切除(cytoreductive nephrectomy, CN)是指尽可能切除转移性肾细胞癌患者的原发灶。晚期转移性肾癌的治疗目前仍是一大难点,治疗方案包括全身治疗和全身治疗联合姑息性手术,减瘤性肾切除主要针对肾肿瘤原发灶的治疗,选择合适的病例及手术时机,对于预后具有重要意义和影响。

Cytoreductive nephrectomy (CN) refers to removing the primary lesion of patients with metastatic renal cell carcinoma as far as possible. At present, the treatment of advanced metastatic renal can-cer is still a major difficulty, and the treatment plan includes systemic therapy and systemic thera-py combined with palliative surgery. Tumor cytoreductive nephrectomy is mainly aimed at the treatment of primary renal tumor. The selection of appropriate cases and surgical timing is of great significance and influence on prognosis.