肝外胆管切除在进展期胆囊癌根治术中临床价值的研究

Clinical Value of Extrahepatic Bile Duct Resection in Advanced Gallbladder Carcinoma

本文章的目的主要是探讨进展期胆囊癌根治术联合肝外胆管切除对患者长期预后的影响。方法:将青海大学附属医院肝胆胰外科2015年1月至2021年12月间收治的经病理诊断为进展期(≥T2期)胆囊癌患者,根据术中是否切除肝外胆管分为胆管切除组(n = 3)和胆管保留组(n = 9)。观察两组病人的临床病理学特征、并发症的发生率及两组患者的预后。结果显示:肝外胆管切除组的中位生存期为33个月,保留组的中位生存期8个月。两组病人生存率有可比性,但是无统计学差异,且肝外胆管切除组的生存率更高。

The purpose of this article is to investigate the long-term prognosis of patients with advanced gallbladder cancer who underwent radical resection combined with extrahepatic bile duct resec-tion. Methods: Patients with advanced stage (≥T2 stage) gallbladder cancer who were admitted to the Department of Hepatobiliary and Pancreatic Surgery of Qinghai University Affiliated Hospital from January 2015 to December 2021 were divided into bile duct resection group (n = 3) and bile duct preservation group (n = 9). The clinicopathological characteristics, the incidence of complica-tions and the prognosis of the two groups of patients were observed. The results showed that the median survival time of extrahepatic bile duct resection group was 33 months, and the median sur-vival time of preservation group was 8 months. The survival rates of the two groups were compara-ble, but not statistically different, and the survival rate of the extrahepatic bile duct resection group was higher.