母乳嗅觉刺激对新生儿操作性疼痛及喂养效果的Meta分析

Effect of Olfactory Stimulation of Breast Milk on Neonatal Operational Pain and Feeding: A Meta-Analysis

目的:评价母乳嗅觉刺激对新生儿操作性疼痛及喂养效果。方法:系统检索从建库至2021年11月期间PubMed、Embase、Web of Science、Cochrane Library、中国生物医学文献数据库、中国知网、维普和万方数据库中有关母乳嗅觉刺激在新生儿护理中应用效果的随机对照试验。采用RevMan 5.3统计软件进行Meta分析。结果:纳入10项研究,共624例新生儿。结果显示,母乳嗅觉刺激能降低新生儿操作性疼痛评分(P 0.05)。根据母乳干预的量进行亚组分析,结果显示2 ml母乳可提高新生儿致痛性操作期间的血氧饱和度(P 0.05)。结论:母乳嗅觉刺激可缓解新生儿操作性疼痛,促进新生儿喂养进程。

Objective: To evaluate the effect of breast milk olfactory stimulation on neonatal operational pain and feeding. Methods: PubMed, Embase, Web of Science, Cochrane Library, CBM, CNKI, VIP and Wanfang database were retrieved for relevant randomized controlled trials of the effect of breast milk olfactory stimulation in neonatal care from the establishment of databasesto November 2021. Meta-analysis was conducted by RevMan 5.3. Results: Totally 10 RCTs involving 624 neonates. The results suggested that breast milk olfactory stimulation could reduce the score of procedural pain of neonates (P 0.05). Subgroup analysis was conducted according to amount of breast milk intervention. The results showed that 2 ml of breast milk could improve the blood oxygen saturation during painful operation (P 0.05). Conclusions: Breast milk olfactory stimulation can alleviate procedural pain and promote the process of neonatal feeding.