摘要
长链非编码RNA在调节基因表达水平上发挥重要的作用,广泛参与人类疾病的进展。LncRNA MAPKAPK5-AS1被发现在多种疾病中处于失调状态,如肝细胞癌、结直肠癌、肺癌及类风湿性关节炎等。本综述总结近些年MAPKAPK5-AS1相关研究,试图揭示其在疾病中的进展机制,为进一步研究提供参考。
Long non-coding RNAs play an important role in the regulation of gene expression levels and are widely involved in the progression of human diseases. LncRNA MAPKAPK5-AS1 has been found to be dysregulated in a variety of diseases, such as hepatocellular carcinoma, colorectal cancer, lung cancer and rheumatoid arthritis. In this review, we summarize the recent progress related to MAPKAPK5-AS1, trying to reveal the mechanism of its progression in the disease, which provided reference for further studies.
出处
《临床医学进展》
2022年第11期10241-10248,共8页
Advances in Clinical Medicine
