老年慢性心力衰竭合并心房颤动的病理生理学及治疗进展

Pathophysiology and Treatment Progress of Elderly Patients with Chronic Heart Failure Complicated with Atrial Fibrillation

心力衰竭(heart failure)是心脏结构和功能异常导致的进行性心脏泵功能障碍的一组临床综合征,是多种心脏疾病的终末阶段,现已经发展成为全球流行疾病,并且随着世界人口老龄化的加深,心力衰竭的发病率及死亡率也逐年上升,构成了重要的全球疾病负担之一。老龄化构比在慢性心力衰竭中呈持续上升趋势,由于其自身临床特点,若合并心房颤动可导致发病率升高、负担费用加大、生活质量降低、心脑血管意外及死亡率增加,且两者可互为因果又相互促进,因此现对老年慢性心力衰竭合并心房颤动的发病机制及诊治进展做进一步展述。

Heart failure is a group of clinical syndromes of progressive heart pump dysfunction caused by ab-normal heart structure and function, and is the end stage of a variety of cardiac diseases that have developed into a global epidemic. As the world’s population ages, the incidence and mortality of heart failure are also increasing year by year, constituting an important global burden of disease. The proportion of aging in chronic heart failure continues to rise. Due to its own clinical characteris-tics, if atrial fibrillation is combined, it can lead to increased morbidity, increased cost, decreased quality of life, increased cardiovascular and cerebrovascular accidents, and increased mortality. The two can cause and promote each other. Therefore, the pathogenesis, diagnosis and treatment pro-gress of chronic heart failure combined with atrial fibrillation in the elderly are further described.