肠道菌群失调与肝癌的相关研究进展

Related Research Progress of Intestinal Flora Imbalance and Hepatocellular Carcinoma

肝细胞癌(HCC,以下简称为肝癌)是我国目前最常见的恶性肿瘤之一,其死亡率在恶性肿瘤中高居第二位。大量研究表明,肠道菌群失调与肝癌的发生、发展存在一定相关性,通过调节肠道菌群治疗肝癌有着光明前景。本文将对肠道菌群失调与肝癌发生、发展的相关性及通过肠道菌群预防及治疗肝癌的研究进展进行综述,希望其未来可以应用至肝癌的筛查、预防及治疗中。

Hepatocellular carcinoma (HCC) is one of the highest malignant tumors in China, the morbidity of HCC tends to go rising to the second level of all the malignant tumors. Numbers of research show that flora imbalance is related to the pathogenesis and progression of hepatocellular carcinoma, and it has a bright prospect to treat hepatocellular carcinoma by regulating gut microbiota. This paper will review the relationship between flora imbalance and the pathogenesis and progression of tumors of hepatocellular carcinoma, and the research progress of prevention and treatment of hepatocellular carcinoma by gut microbiota, hoping that it can be applied to the screening, pre-vention and treatment of hepatocellular carcinoma in the future.