纳米银治疗感染性角膜炎的作用机制研究进展

Research Advances on the Mechanism of AgNPs in the Treatment of Infectious Keratitis

感染性角膜炎是我国致盲眼病的重要原因,针对难治性的感染性角膜炎,传统的抗菌药物难以达到良好的治疗效果,纳米银具有较大的比表面积、较强的渗透力、耐氧化性和无耐药性,具有良好的抗微生物效果。本文就当前纳米抗微生物治疗感染性角膜炎的作用机制、应用前景进行综述。

Infectious keratitis is an important cause of blindness in China. For refractory infectious keratitis, traditional antibacterial drugs are difficult to achieve good therapeutic effects, and nanosilver has a large specific surface area, strong permeability, oxidation resistance and no drug resistance, and has good anti-microbial effects. This article reviews the current mechanism of action and prospects for the application of nano-antimicrobial therapy for infectious keratitis.