补阳还五汤治疗特发性肺纤维化研究进展

Research Progress of Buyang Huanwu Decoction in the Treatment of Pulmonary Fibrosis

IPF是一种原因不明的慢性、进行性、不可逆性间质性肺疾病,现代医学以糖皮质激素及免疫抑制剂治疗为主,但难以解决肺部纤维化的根本问题。补阳还五汤作为益气活血通络的代表方剂,因其在治疗IPF方面疗效突出而受到重视。本文通过梳理IPF中医病因病机及现代医学发病机制、补阳还五汤理论研究、补阳还五汤治疗IPF的临床疗效观察等,使补阳还五汤在IPF实际临床治疗中发挥更大的作用。

IPF is a chronic, progressive and irreversible interstitial lung disease of unknown cause, and mod-ern medicine is mainly treated with glucocorticoids and immunosuppressants, but it is difficult to solve the fundamental problem of pulmonary fibrosis. As a representative prescription for Yiqi Hu-oxue Tongluo Method, Buyang Huanwu decoction has been valued for its outstanding efficacy in the treatment of IPF. In this paper, by combing the etiology and pathogenesis of IPF in traditional Chi-nese medicine and the pathogenesis of modern medicine, the theoretical research on the theory of Buyang Huanwu decoction, and the observation of the clinical efficacy of Buyang Huanwu decoction in the treatment of IPF, this paper makes the Buyang Huanwu decoction play a greater role in the actual clinical treatment of IPF.