脂蛋白a与冠状动脉慢血流现象的关系

Relationship between Lipoprotein a and Coronary Slow Flow Phenomenon

目的:众多研究已证实脂蛋白a[Lp(a)]是冠心病的重要风险因素,冠状动脉慢血流现象(coronary slow flow phenomenon, CSFP)是一个真实存在的血管造影现象,目前两者之间关系尚不清楚。因此我们旨在研究Lp(a)和CSFP之间的关系。方法:选取我院2019年7月~2022年7月因疑似冠状动脉疾病接受冠状动脉造影检查发现CSFP的患者120例作为CSFP组,随机选取120例冠脉血流正常患者作为Non-CSFP组。比较两组患者临床资料及相关实验室检查指标。结论:Lp(a)是CSFP独立风险因素,其浓度随着涉及血管数量的增加而增加,Lp(a)可以预测CSFP的发生和严重程度。

Objective: Many studies have confirmed that lipoprotein a is an important risk factor of coronary heart disease, and coronary slow flow phenomenon (CSFP) is a real angiography phenomenon. At present, the relationship between the two remains unclear. Therefore, we aim to study the rela-tionship between Lp(a) and CSFP. Methods: A total of 120 patients with CSFP detected by coronary angiography in our hospital from July 2019 to July 2022 due to suspected coronary artery disease were selected as the CSFP group, and 120 patients with normal coronary blood flow were randomly selected as the Non-CSFP group. The clinical data and related laboratory test indexes were com-pared between the two groups. Conclusion: Lp(a) is an independent risk factor for CSFP, and its concentration increases with the number of involved vessels. Lp(a) can predict the occurrence and severity of CSFP.